“I don’t feel any different after taking this medication. In the process, we hear the following questions most often from patients: The ADHD medication isn’t working. Most of the work of ADHD prescribers involves adjusting this titration, especially in the early weeks. A 1998 study by the American Medical Association 1 found that 90 percent of children with attention deficit hyperactivity disorder (ADHD or ADD) responded to at least one stimulant without any significant side effects if the drug is carefully fine-tuned by the clinician. There are more research studies done on these types of medicines than on any other medicine you will ever take. Amphetamine has been around since 1937, and methylphenidate since 1956. Studies show that ADHD medication safely and effectively improves communication between neurons in the ADHD brain. Stimulants improve communication between neurons. This is the specific problem that ADHD medications solve. Some messages do not make the link from one neuron to another, and that’s where attention and impulsivity problems arise. The ADHD brain makes neurotransmitters just like everybody else’s brain, but often it does not release and reload the chemicals - primarily dopamine - effectively. This is where ADHD brains run into trouble. The brain chemicals powering the operation are called neurotransmitters - for example, dopamine and norepinephrine. On the other side, another neuron waits to receive the information. A single neuron may deliver 12 messages in one-thousandth of a second by using tiny chemical impulses to leap over tinier gaps called synapses. The 100 billion neurons in your brain are always busy.
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